7.6 Prevalence and Correlates of Childhood-Onset Bipolar Disorder Among Adolescents

Early-onset bipolar disorder (BD) is associated with a more severe illness as well number of clinical factors among adults. can be categorized childhood-onset (age <13 years) or adolescent-onset ≥13 years), the 2 displaying different profiles. However, adolescents, there paucity research comparing both prevalence and profiles to BD. We set out examine potential differences in demographic, clinical, familial characteristics adolescents childhood- vs The study included 195 BD, ages 14 18 years. age onset was determined retrospectively by self-report. Participants completed semi-structured K-SADS Present Lifetime Version (K-SADS-PL) diagnostic interviews along self-reported dimensional scales. Analyses examined between-group variables, individual manic depressive symptom severity for most past episodes. Variables that were at p < 0.1 univariate analyses evaluated logistic regression model. Approximately one-fifth participants had BD (n = 35; 17.9%). A demographic significantly no significant depression mania severity. In multivariate analyses, variables strongly police contact, stimulant treatment, family history suicidal ideation (positively associated), smoking psychiatric hospitalization (negatively associated). this large sample reported Correlates generally aligned those observed literature, majority which age-related. lack particularly noteworthy. Future warranted better understand genetic environmental implications high loading psychopathology integrate age-related treatment prevention strategies.